Rebuilt over the next two centuries (with long gaps between construction stages), the old cathedral was completely replaced. However, this construction also had some faults; in 1754, a large stone fell from the roof of the choir. It was then decided to demolish everything before the whole building collapsed. This demolition occurred between 1756 and 1768, leaving just the formerly rebuilt tower and western facade intact. Rebuilding began in 1787 but was suspended when the French Revolution took place. By 1816, reconstruction began again., finishing by 1845. During this period of reconstruction, the Abbey church “Our Lady in Saint Melanie of Rennes” served as the pro-cathedral (i.e. temporary substitute). This Abbey church had been dedicated to the first bishop of Rennes (St. Melanie) who was buried on the grounds in the sixth century.
During 1906, the Cathedral was designated as a historic monument since it was the only church in Breton modeled after a Roman Basilica. The coronations of all the Dukes and Duchess of Brittany have occurred in this Cathedral.